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Found 1 hit Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Ligand = 'BDBM50251311'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50251311
PNG
(CHEMBL4104755)
Show SMILES Cc1cc(=O)n(nc1C(=O)Nc1ccc(Oc2ccnc3[nH]ccc23)cc1)-c1ccc(F)cc1
Show InChI InChI=1S/C25H18FN5O3/c1-15-14-22(32)31(18-6-2-16(26)3-7-18)30-23(15)25(33)29-17-4-8-19(9-5-17)34-21-11-13-28-24-20(21)10-12-27-24/h2-14H,1H3,(H,27,28)(H,29,33)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 8.40n/an/an/an/an/an/a



School of Pharmacy, Jiangxi Science and Technology Normal University, Nanchang 330013, PR China. Electronic address: tangqidongcn@126.com.

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay


Eur J Med Chem 133: 97-106 (2017)


Article DOI: 10.1016/j.ejmech.2017.03.045
BindingDB Entry DOI: 10.7270/Q2K35X3B
More data for this
Ligand-Target Pair