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Found 1 hit Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Ligand = 'BDBM50251332'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50251332
PNG
(CHEMBL4102463)
Show SMILES Cc1cc(=O)n(nc1C(=O)Nc1ccc(Oc2ccnc3[nH]ccc23)c(F)c1)-c1ccccc1C(F)(F)F
Show InChI InChI=1S/C26H17F4N5O3/c1-14-12-22(36)35(19-5-3-2-4-17(19)26(28,29)30)34-23(14)25(37)33-15-6-7-21(18(27)13-15)38-20-9-11-32-24-16(20)8-10-31-24/h2-13H,1H3,(H,31,32)(H,33,37)
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Similars
Article
PubMed
n/an/a 11n/an/an/an/an/an/a



School of Pharmacy, Jiangxi Science and Technology Normal University, Nanchang 330013, PR China. Electronic address: tangqidongcn@126.com.

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay

Eur J Med Chem 133: 97-106 (2017)


Article DOI: 10.1016/j.ejmech.2017.03.045
BindingDB Entry DOI: 10.7270/Q2K35X3B
More data for this
Ligand-Target Pair