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Found 1 hit Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Ligand = 'BDBM50306679'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50306679
PNG
(CHEMBL608738 | rac-3-(6-(1-(2,6-dichloro-3-fluorop...)
Show SMILES CC(Oc1ccc2ncc(\C=C\C(=O)N(C)C)cc2c1)c1c(Cl)ccc(F)c1Cl
Show InChI InChI=1S/C22H19Cl2FN2O2/c1-13(21-17(23)6-7-18(25)22(21)24)29-16-5-8-19-15(11-16)10-14(12-26-19)4-9-20(28)27(2)3/h4-13H,1-3H3/b9-4+
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Article
PubMed
n/an/a 59n/an/an/an/an/an/a



Chugai Pharmaceutical Co, Ltd

Curated by ChEMBL


Assay Description
Inhibition of recombinant c-Met by TR-FRET assay

Bioorg Med Chem Lett 20: 1405-9 (2010)


Article DOI: 10.1016/j.bmcl.2009.12.109
BindingDB Entry DOI: 10.7270/Q2HQ401G
More data for this
Ligand-Target Pair