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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Ligand = 'BDBM50352761'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50352761
PNG
(CHEMBL1823361 | US9126931, 353)
Show SMILES CC1(C)c2[nH]c3cc(ccc3c2C(=O)c2cc(CCC3CCCC3)c(cc12)N1CCN(CC1)C1COC1)C#N
Show InChI InChI=1S/C33H38N4O2/c1-33(2)27-17-29(37-13-11-36(12-14-37)24-19-39-20-24)23(9-7-21-5-3-4-6-21)16-26(27)31(38)30-25-10-8-22(18-34)15-28(25)35-32(30)33/h8,10,15-17,21,24,35H,3-7,9,11-14,19-20H2,1-2H3
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Similars
Article
PubMed
n/an/a>5.00E+3n/an/an/an/an/an/a



Chugai Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of MET activity by TR-FRET assay

J Med Chem 54: 6286-94 (2011)


Article DOI: 10.1021/jm200652u
BindingDB Entry DOI: 10.7270/Q2P55NWZ
More data for this
Ligand-Target Pair