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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Ligand = 'BDBM50383210'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50383210
PNG
(CHEMBL2032034)
Show SMILES COc1cc2nccc(Oc3ccc(NC(=O)C4(C)CCN(C4=O)c4ccccc4)cc3F)c2cc1OC
Show InChI InChI=1S/C29H26FN3O5/c1-29(12-14-33(28(29)35)19-7-5-4-6-8-19)27(34)32-18-9-10-24(21(30)15-18)38-23-11-13-31-22-17-26(37-3)25(36-2)16-20(22)23/h4-11,13,15-17H,12,14H2,1-3H3,(H,32,34)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
56.7n/an/an/an/an/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Inhibition of recombinant c-met-mediated gastrin phosphorylation by HTRF assay


J Med Chem 55: 1858-67 (2012)


Article DOI: 10.1021/jm201330u
BindingDB Entry DOI: 10.7270/Q2ZK5HQP
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50383210
PNG
(CHEMBL2032034)
Show SMILES COc1cc2nccc(Oc3ccc(NC(=O)C4(C)CCN(C4=O)c4ccccc4)cc3F)c2cc1OC
Show InChI InChI=1S/C29H26FN3O5/c1-29(12-14-33(28(29)35)19-7-5-4-6-8-19)27(34)32-18-9-10-24(21(30)15-18)38-23-11-13-31-22-17-26(37-3)25(36-2)16-20(22)23/h4-11,13,15-17H,12,14H2,1-3H3,(H,32,34)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 667n/an/an/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Inhibition of HGF-mediated c-met autophosphorylation in serum-starved human PC3 cells after 1 hr by electrochemiluminescent immunoassay


J Med Chem 55: 1858-67 (2012)


Article DOI: 10.1021/jm201330u
BindingDB Entry DOI: 10.7270/Q2ZK5HQP
More data for this
Ligand-Target Pair