Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Ligand = 'BDBM50387355'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Canis familiaris)	BDBM50387355 (CHEMBL2046801) Show SMILES FC(F)(F)c1cc(CC(=O)NC(Cc2ccccc2)c2cn(nn2)-c2ccc(cc2)-c2cn3c(n2)sc2ccccc32)cc(c1)C(F)(F)F Show InChI InChI=1S/C35H24F6N6OS/c36-34(37,38)24-14-22(15-25(18-24)35(39,40)41)17-32(48)42-27(16-21-6-2-1-3-7-21)29-20-47(45-44-29)26-12-10-23(11-13-26)28-19-46-30-8-4-5-9-31(30)49-33(46)43-28/h1-15,18-20,27H,16-17H2,(H,42,48)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Inhibition of Met-triggered cell scattering in HGF-stimulated MDCK cells preincubated for overnight before HGF challenge measured after 24 to 48 hrs				Bioorg Med Chem Lett 22: 4693-6 (2012) Article DOI: 10.1016/j.bmcl.2012.05.078 BindingDB Entry DOI: 10.7270/Q2PV6MF0
					More data for this Ligand-Target Pair