Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'High affinity nerve growth factor receptor' and Ligand = 'BDBM356097'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM356097 (N-(2-((2,4-dioxooxazolidin-3- yl)methyl)-4-phenylp...) Show SMILES Cn1ccc(n1)-c1cc(C(=O)Nc2cnc(CN3C(=O)COC3=O)nc2-c2ccccc2)c(F)cc1C(F)(F)F Show InChI InChI=1S/C26H18F4N6O4/c1-35-8-7-19(34-35)15-9-16(18(27)10-17(15)26(28,29)30)24(38)32-20-11-31-21(12-36-22(37)13-40-25(36)39)33-23(20)14-5-3-2-4-6-14/h2-11H,12-13H2,1H3,(H,32,38)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.25	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...				US Patent US9815846 (2017) BindingDB Entry DOI: 10.7270/Q20P129R
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