Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM50118955 (CHEMBL94678 | Compound K-252a(epi)) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc. Curated by ChEMBL | Assay Description Inhibition of nerve growth factor receptor, trkA | Bioorg Med Chem Lett 12: 2829-31 (2002) BindingDB Entry DOI: 10.7270/Q2Z037H2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM50118955 (CHEMBL94678 | Compound K-252a(epi)) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc. Curated by ChEMBL | Assay Description Inhibition of baculovirus expressed human trkA | J Med Chem 48: 3776-83 (2005) Article DOI: 10.1021/jm040178m BindingDB Entry DOI: 10.7270/Q2HX1C66 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM50118955 (CHEMBL94678 | Compound K-252a(epi)) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc. Curated by ChEMBL | Assay Description Inhibition of NGF-stimulated TrkA phosphorylation in NIH3T3 cells | J Med Chem 48: 3776-83 (2005) Article DOI: 10.1021/jm040178m BindingDB Entry DOI: 10.7270/Q2HX1C66 | |||||||||||
More data for this Ligand-Target Pair |