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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'High affinity nerve growth factor receptor' and Ligand = 'BDBM50384732'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
High affinity nerve growth factor receptor


(Homo sapiens (Human))
BDBM50384732
PNG
(CHEMBL2037213)
Show SMILES OC1CCN(CC1)c1cc(cc(c1)C(F)(F)F)C(=O)Nc1cccc(Nc2ccc3\C(=C\c4ccc[nH]4)C(=O)Nc3c2)c1
Show InChI InChI=1S/C32H28F3N5O3/c33-32(34,35)20-13-19(14-25(15-20)40-11-8-26(41)9-12-40)30(42)38-23-4-1-3-22(16-23)37-24-6-7-27-28(17-21-5-2-10-36-21)31(43)39-29(27)18-24/h1-7,10,13-18,26,36-37,41H,8-9,11-12H2,(H,38,42)(H,39,43)/b28-17-
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of TRKA by HTRF assay


ACS Med Chem Lett 3: 140-145 (2012)


Article DOI: 10.1021/ml200261d
BindingDB Entry DOI: 10.7270/Q2SJ1MNM
More data for this
Ligand-Target Pair