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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine H1 receptor' and Ligand = 'BDBM50146354'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H1 receptor


(Homo sapiens (Human))		BDBM50146354
PNG
(2-{4-[(3aR,12bS)-1-(3,3a,8,12b-Tetrahydro-2H-1-oxa...)
Show SMILES OCCN1CCN(CC2C[C@H]3[C@H](O2)c2ccccc2Cc2ccccc32)CC1
Show InChI InChI=1S/C24H30N2O2/c27-14-13-25-9-11-26(12-10-25)17-20-16-23-21-7-3-1-5-18(21)15-19-6-2-4-8-22(19)24(23)28-20/h1-8,20,23-24,27H,9-17H2/t20?,23-,24-/m1/s1
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Similars
Article
PubMed
 3.70n/an/an/an/an/an/an/an/a



Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL


Assay Description
Ability to displace [3H]-pyrilamine from human cloned histamine H1 receptor expressed in CHO cells

Bioorg Med Chem Lett 14: 2765-71 (2004)


Article DOI: 10.1016/j.bmcl.2004.03.069
BindingDB Entry DOI: 10.7270/Q21835ZF
More data for this
Ligand-Target Pair