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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine H1 receptor' and Ligand = 'BDBM50156856'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H1 receptor


(Cavia porcellus (domestic guinea pig))
BDBM50156856
PNG
(2-(2-(4-(1-(2-ethoxyethyl)-1H-indol-3-yl)piperidin...)
Show SMILES CCOCCn1cc(C2CCN(CCOc3ccc(C)cc3C(O)=O)CC2)c2ccccc12
Show InChI InChI=1S/C27H34N2O4/c1-3-32-16-15-29-19-24(22-6-4-5-7-25(22)29)21-10-12-28(13-11-21)14-17-33-26-9-8-20(2)18-23(26)27(30)31/h4-9,18-19,21H,3,10-17H2,1-2H3,(H,30,31)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 221n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Displacement of [3H]mepyramine from histamine H1 receptor in guinea pig cerebellum membranes


J Med Chem 47: 6326-37 (2004)


Article DOI: 10.1021/jm0498203
BindingDB Entry DOI: 10.7270/Q2HM57XC
More data for this
Ligand-Target Pair