Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Histamine H1 receptor' and Ligand = 'BDBM50419324'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H1 receptor (Homo sapiens (Human))	BDBM50419324 (CHEMBL1910384) Show SMILES COc1ccc(CN(CCN[C@H]2CCN(C2)C(=O)c2cc3ccccc3[nH]2)c2ccccn2)cc1 |r| Show InChI InChI=1S/C28H31N5O2/c1-35-24-11-9-21(10-12-24)19-32(27-8-4-5-14-30-27)17-15-29-23-13-16-33(20-23)28(34)26-18-22-6-2-3-7-25(22)31-26/h2-12,14,18,23,29,31H,13,15-17,19-20H2,1H3/t23-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	457	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Displacement of [3H]mepyramine from human H1R expressed in Sf9 cells co-expressing RGS4 after 90 mins by liquid scintillation counting				Bioorg Med Chem Lett 21: 6274-80 (2011) Article DOI: 10.1016/j.bmcl.2011.09.001 BindingDB Entry DOI: 10.7270/Q28K7BB7
					More data for this Ligand-Target Pair
Histamine H1 receptor (Cavia porcellus (domestic guinea pig))	BDBM50419324 (CHEMBL1910384) Show SMILES COc1ccc(CN(CCN[C@H]2CCN(C2)C(=O)c2cc3ccccc3[nH]2)c2ccccn2)cc1 |r| Show InChI InChI=1S/C28H31N5O2/c1-35-24-11-9-21(10-12-24)19-32(27-8-4-5-14-30-27)17-15-29-23-13-16-33(20-23)28(34)26-18-22-6-2-3-7-25(22)31-26/h2-12,14,18,23,29,31H,13,15-17,19-20H2,1H3/t23-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	8.51	n/a	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Antagonist activity at H1R in guinea pig ileum assessed as inhibition of histamine-induced muscle contraction after 15 mins				Bioorg Med Chem Lett 21: 6274-80 (2011) Article DOI: 10.1016/j.bmcl.2011.09.001 BindingDB Entry DOI: 10.7270/Q28K7BB7
					More data for this Ligand-Target Pair