Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine H3 receptor' and Ligand = 'BDBM108281'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Macaca mulatta (Rhesus macaque))	BDBM108281 (US8604046, 61) Show SMILES CC(C)(C)OC(=O)N1CCC2(CCCN(C2=O)c2ccc(cc2F)N2CC[C@@H](C2)N2CCCC2)CC1 |r| Show InChI InChI=1S/C28H41FN4O3/c1-27(2,3)36-26(35)31-17-11-28(12-18-31)10-6-15-33(25(28)34)24-8-7-21(19-23(24)29)32-16-9-22(20-32)30-13-4-5-14-30/h7-8,19,22H,4-6,9-18,20H2,1-3H3/t22-/m0/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.0300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The compounds of this invention have been demonstrated to displace [3H]- methylhistamine radioligand binding to mammalian cell membranes expressing r...				US Patent US8604046 (2013) BindingDB Entry DOI: 10.7270/Q2W957TB
					More data for this Ligand-Target Pair