Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine H3 receptor' and Ligand = 'BDBM108293'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Macaca mulatta (Rhesus macaque))	BDBM108293 (US8604046, 73) Show SMILES C[C@H]1CCCN1[C@H]1CCN(C1)c1ccc(cc1)N1CCCC2(CCN(CC3CC3)CC2)C1=O |r| Show InChI InChI=1S/C28H42N4O/c1-22-4-2-15-31(22)26-11-17-30(21-26)24-7-9-25(10-8-24)32-16-3-12-28(27(32)33)13-18-29(19-14-28)20-23-5-6-23/h7-10,22-23,26H,2-6,11-21H2,1H3/t22-,26-/m0/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The compounds of this invention have been demonstrated to displace [3H]- methylhistamine radioligand binding to mammalian cell membranes expressing r...				US Patent US8604046 (2013) BindingDB Entry DOI: 10.7270/Q2W957TB
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