Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine H3 receptor' and Ligand = 'BDBM108305'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Macaca mulatta (Rhesus macaque))	BDBM108305 (US8604046, 85) Show SMILES C[C@H]1CCCN1C1CCN(CC1)c1ccc(N2CCC3(CCNCC3)C2=O)c(F)c1 |r| Show InChI InChI=1S/C24H35FN4O/c1-18-3-2-13-28(18)19-6-14-27(15-7-19)20-4-5-22(21(25)17-20)29-16-10-24(23(29)30)8-11-26-12-9-24/h4-5,17-19,26H,2-3,6-16H2,1H3/t18-/m0/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The compounds of this invention have been demonstrated to displace [3H]- methylhistamine radioligand binding to mammalian cell membranes expressing r...				US Patent US8604046 (2013) BindingDB Entry DOI: 10.7270/Q2W957TB
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