Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Histamine H3 receptor' and Ligand = 'BDBM50050166'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50050166 (4-Iodo-benzoic acid 3-(1H-imidazol-4-yl)-propyl es...) Show SMILES Ic1ccc(cc1)C(=O)OCCCc1cnc[nH]1 Show InChI InChI=1S/C13H13IN2O2/c14-11-5-3-10(4-6-11)13(17)18-7-1-2-12-8-15-9-16-12/h3-6,8-9H,1-2,7H2,(H,15,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Binding affinity towards Histamine H3 receptor on synaptosomes from rat cerebral cortex				J Med Chem 39: 1220-6 (1996) Article DOI: 10.1021/jm9504767 BindingDB Entry DOI: 10.7270/Q28K7855
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50050166 (4-Iodo-benzoic acid 3-(1H-imidazol-4-yl)-propyl es...) Show SMILES Ic1ccc(cc1)C(=O)OCCCc1cnc[nH]1 Show InChI InChI=1S/C13H13IN2O2/c14-11-5-3-10(4-6-11)13(17)18-7-1-2-12-8-15-9-16-12/h3-6,8-9H,1-2,7H2,(H,15,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	19.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description In vitro antagonistic activity tested against Histamine H3 receptor on synaptosomes from rat cerebral cortex				J Med Chem 39: 1220-6 (1996) Article DOI: 10.1021/jm9504767 BindingDB Entry DOI: 10.7270/Q28K7855
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50050166 (4-Iodo-benzoic acid 3-(1H-imidazol-4-yl)-propyl es...) Show SMILES Ic1ccc(cc1)C(=O)OCCCc1cnc[nH]1 Show InChI InChI=1S/C13H13IN2O2/c14-11-5-3-10(4-6-11)13(17)18-7-1-2-12-8-15-9-16-12/h3-6,8-9H,1-2,7H2,(H,15,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description In vitro antagonistic activity tested against Histamine H3 receptor on synaptosomes from rat cerebral cortex				J Med Chem 39: 1220-6 (1996) Article DOI: 10.1021/jm9504767 BindingDB Entry DOI: 10.7270/Q28K7855
					More data for this Ligand-Target Pair