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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine H3 receptor' and Ligand = 'BDBM50092867'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H3 receptor


(Rattus norvegicus (rat))		BDBM50092867
PNG
(4-(8-Fluoro-1,3,4,5-tetrahydro-pyrido[4,3-b]indol-...)
Show SMILES Fc1ccc2[nH]c3CCN(CCCC(=O)c4ccc(OCCCc5cnc[nH]5)cc4)Cc3c2c1
Show InChI InChI=1S/C27H29FN4O2/c28-20-7-10-25-23(15-20)24-17-32(13-11-26(24)31-25)12-1-4-27(33)19-5-8-22(9-6-19)34-14-2-3-21-16-29-18-30-21/h5-10,15-16,18,31H,1-4,11-14,17H2,(H,29,30)
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 410n/an/an/an/an/an/an/an/a



Freie Universit£t Berlin

Curated by ChEMBL


Assay Description
Effect on histamine H3 receptors in vitro, on synaptosomes of rat cerebral cortex for the release of [3H]histamine

J Med Chem 43: 3987-94 (2000)


BindingDB Entry DOI: 10.7270/Q2833SRN
More data for this
Ligand-Target Pair