Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Histamine H3 receptor' and Ligand = 'BDBM50268450'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50268450 ((5-(1-isopropylpiperidin-4-ylamino)-1H-indol-2-yl)...) Show SMILES CC(C)N1CCC(CC1)Nc1ccc2[nH]c(cc2c1)C(=O)N1CCOCC1 Show InChI InChI=1S/C21H30N4O2/c1-15(2)24-7-5-17(6-8-24)22-18-3-4-19-16(13-18)14-20(23-19)21(26)25-9-11-27-12-10-25/h3-4,13-15,17,22-23H,5-12H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Displacement of [3H](R)-alpha-methylhistamine from rat recombinant histamine H3 receptor expressed in CHO cells by liquid scintillation counting				J Med Chem 52: 3855-68 (2009) Article DOI: 10.1021/jm900409x BindingDB Entry DOI: 10.7270/Q2SB46NQ
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50268450 ((5-(1-isopropylpiperidin-4-ylamino)-1H-indol-2-yl)...) Show SMILES CC(C)N1CCC(CC1)Nc1ccc2[nH]c(cc2c1)C(=O)N1CCOCC1 Show InChI InChI=1S/C21H30N4O2/c1-15(2)24-7-5-17(6-8-24)22-18-3-4-19-16(13-18)14-20(23-19)21(26)25-9-11-27-12-10-25/h3-4,13-15,17,22-23H,5-12H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	64	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Displacement of [3H](R)-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in CHO cells by liquid scintillation counting				J Med Chem 52: 3855-68 (2009) Article DOI: 10.1021/jm900409x BindingDB Entry DOI: 10.7270/Q2SB46NQ
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50268450 ((5-(1-isopropylpiperidin-4-ylamino)-1H-indol-2-yl)...) Show SMILES CC(C)N1CCC(CC1)Nc1ccc2[nH]c(cc2c1)C(=O)N1CCOCC1 Show InChI InChI=1S/C21H30N4O2/c1-15(2)24-7-5-17(6-8-24)22-18-3-4-19-16(13-18)14-20(23-19)21(26)25-9-11-27-12-10-25/h3-4,13-15,17,22-23H,5-12H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	44	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Inverse agonist activity at human histamine H3 receptor expressed in CHO cells by GTPgamma[35S] binding assay				J Med Chem 52: 3855-68 (2009) Article DOI: 10.1021/jm900409x BindingDB Entry DOI: 10.7270/Q2SB46NQ
					More data for this Ligand-Target Pair