Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Histamine H3 receptor' and Ligand = 'BDBM50268452'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50268452 ((4-cyclobutylpiperazin-1-yl)(2-(morpholine-4-carbo...) Show SMILES FC(F)(F)Cn1c(cc2cc(ccc12)C(=O)N1CCN(CC1)C1CCC1)C(=O)N1CCOCC1 Show InChI InChI=1S/C24H29F3N4O3/c25-24(26,27)16-31-20-5-4-17(22(32)29-8-6-28(7-9-29)19-2-1-3-19)14-18(20)15-21(31)23(33)30-10-12-34-13-11-30/h4-5,14-15,19H,1-3,6-13,16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Displacement of [3H](R)-alpha-methylhistamine from rat recombinant histamine H3 receptor expressed in CHO cells by liquid scintillation counting				J Med Chem 52: 3855-68 (2009) Article DOI: 10.1021/jm900409x BindingDB Entry DOI: 10.7270/Q2SB46NQ
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50268452 ((4-cyclobutylpiperazin-1-yl)(2-(morpholine-4-carbo...) Show SMILES FC(F)(F)Cn1c(cc2cc(ccc12)C(=O)N1CCN(CC1)C1CCC1)C(=O)N1CCOCC1 Show InChI InChI=1S/C24H29F3N4O3/c25-24(26,27)16-31-20-5-4-17(22(32)29-8-6-28(7-9-29)19-2-1-3-19)14-18(20)15-21(31)23(33)30-10-12-34-13-11-30/h4-5,14-15,19H,1-3,6-13,16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Displacement of [3H](R)-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in CHO cells by liquid scintillation counting				J Med Chem 52: 3855-68 (2009) Article DOI: 10.1021/jm900409x BindingDB Entry DOI: 10.7270/Q2SB46NQ
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50268452 ((4-cyclobutylpiperazin-1-yl)(2-(morpholine-4-carbo...) Show SMILES FC(F)(F)Cn1c(cc2cc(ccc12)C(=O)N1CCN(CC1)C1CCC1)C(=O)N1CCOCC1 Show InChI InChI=1S/C24H29F3N4O3/c25-24(26,27)16-31-20-5-4-17(22(32)29-8-6-28(7-9-29)19-2-1-3-19)14-18(20)15-21(31)23(33)30-10-12-34-13-11-30/h4-5,14-15,19H,1-3,6-13,16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Inverse agonist activity at human histamine H3 receptor expressed in CHO cells by GTPgamma[35S] binding assay				J Med Chem 52: 3855-68 (2009) Article DOI: 10.1021/jm900409x BindingDB Entry DOI: 10.7270/Q2SB46NQ
					More data for this Ligand-Target Pair