Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Histamine H3 receptor' and Ligand = 'BDBM50268948'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50268948 ((5-(1-tert-butylpiperidin-4-yloxy)-1H-indol-2-yl)(...) Show SMILES CC(C)(C)N1CCC(CC1)Oc1ccc2[nH]c(cc2c1)C(=O)N1CCOCC1 Show InChI InChI=1S/C22H31N3O3/c1-22(2,3)25-8-6-17(7-9-25)28-18-4-5-19-16(14-18)15-20(23-19)21(26)24-10-12-27-13-11-24/h4-5,14-15,17,23H,6-13H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Displacement of [3H](R)-alpha-methylhistamine from rat recombinant histamine H3 receptor expressed in CHO cells by liquid scintillation counting				J Med Chem 52: 3855-68 (2009) Article DOI: 10.1021/jm900409x BindingDB Entry DOI: 10.7270/Q2SB46NQ
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50268948 ((5-(1-tert-butylpiperidin-4-yloxy)-1H-indol-2-yl)(...) Show SMILES CC(C)(C)N1CCC(CC1)Oc1ccc2[nH]c(cc2c1)C(=O)N1CCOCC1 Show InChI InChI=1S/C22H31N3O3/c1-22(2,3)25-8-6-17(7-9-25)28-18-4-5-19-16(14-18)15-20(23-19)21(26)24-10-12-27-13-11-24/h4-5,14-15,17,23H,6-13H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Displacement of [3H](R)-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in CHO cells by liquid scintillation counting				J Med Chem 52: 3855-68 (2009) Article DOI: 10.1021/jm900409x BindingDB Entry DOI: 10.7270/Q2SB46NQ
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50268948 ((5-(1-tert-butylpiperidin-4-yloxy)-1H-indol-2-yl)(...) Show SMILES CC(C)(C)N1CCC(CC1)Oc1ccc2[nH]c(cc2c1)C(=O)N1CCOCC1 Show InChI InChI=1S/C22H31N3O3/c1-22(2,3)25-8-6-17(7-9-25)28-18-4-5-19-16(14-18)15-20(23-19)21(26)24-10-12-27-13-11-24/h4-5,14-15,17,23H,6-13H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Inverse agonist activity at human histamine H3 receptor expressed in CHO cells by GTPgamma[35S] binding assay				J Med Chem 52: 3855-68 (2009) Article DOI: 10.1021/jm900409x BindingDB Entry DOI: 10.7270/Q2SB46NQ
					More data for this Ligand-Target Pair