Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Histamine H3 receptor' and Ligand = 'BDBM50268994'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50268994 ((5-(1-isopropylpiperidin-4-yloxy)-1H-indol-2-yl)(4...) Show SMILES COC1CCN(CC1)C(=O)c1cc2cc(OC3CCN(CC3)C(C)C)ccc2[nH]1 Show InChI InChI=1S/C23H33N3O3/c1-16(2)25-10-8-19(9-11-25)29-20-4-5-21-17(14-20)15-22(24-21)23(27)26-12-6-18(28-3)7-13-26/h4-5,14-16,18-19,24H,6-13H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Displacement of [3H](R)-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in CHO cells by liquid scintillation counting				J Med Chem 52: 3855-68 (2009) Article DOI: 10.1021/jm900409x BindingDB Entry DOI: 10.7270/Q2SB46NQ
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50268994 ((5-(1-isopropylpiperidin-4-yloxy)-1H-indol-2-yl)(4...) Show SMILES COC1CCN(CC1)C(=O)c1cc2cc(OC3CCN(CC3)C(C)C)ccc2[nH]1 Show InChI InChI=1S/C23H33N3O3/c1-16(2)25-10-8-19(9-11-25)29-20-4-5-21-17(14-20)15-22(24-21)23(27)26-12-6-18(28-3)7-13-26/h4-5,14-16,18-19,24H,6-13H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Displacement of [3H](R)-alpha-methylhistamine from rat recombinant histamine H3 receptor expressed in CHO cells by liquid scintillation counting				J Med Chem 52: 3855-68 (2009) Article DOI: 10.1021/jm900409x BindingDB Entry DOI: 10.7270/Q2SB46NQ
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50268994 ((5-(1-isopropylpiperidin-4-yloxy)-1H-indol-2-yl)(4...) Show SMILES COC1CCN(CC1)C(=O)c1cc2cc(OC3CCN(CC3)C(C)C)ccc2[nH]1 Show InChI InChI=1S/C23H33N3O3/c1-16(2)25-10-8-19(9-11-25)29-20-4-5-21-17(14-20)15-22(24-21)23(27)26-12-6-18(28-3)7-13-26/h4-5,14-16,18-19,24H,6-13H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	9	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Inverse agonist activity at human histamine H3 receptor expressed in CHO cells by GTPgamma[35S] binding assay				J Med Chem 52: 3855-68 (2009) Article DOI: 10.1021/jm900409x BindingDB Entry DOI: 10.7270/Q2SB46NQ
					More data for this Ligand-Target Pair