Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Histamine H3 receptor (Homo sapiens (Human)) | BDBM50328813 (CHEMBL1270265 | rac-1,2,5-trimethyl-4-(quinolin-8-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 709 | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys Inc. Curated by ChEMBL | Assay Description Antagonist activity against human histamine H3 receptor expressed in human HT1080 cells assessed as inhibition of (R)-alpha-methylhistamine-induced i... | Bioorg Med Chem Lett 20: 6246-9 (2010) Article DOI: 10.1016/j.bmcl.2010.08.099 BindingDB Entry DOI: 10.7270/Q2DF6RGG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (Mus musculus) | BDBM50328813 (CHEMBL1270265 | rac-1,2,5-trimethyl-4-(quinolin-8-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 9.73E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys Inc. Curated by ChEMBL | Assay Description Antagonist activity against mouse histamine H3 receptor expressed in human HT1080 cells assessed as inhibition of (R)-alpha-methylhistamine-induced i... | Bioorg Med Chem Lett 20: 6246-9 (2010) Article DOI: 10.1016/j.bmcl.2010.08.099 BindingDB Entry DOI: 10.7270/Q2DF6RGG | |||||||||||
More data for this Ligand-Target Pair |