Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Histamine H4 receptor' and Ligand = 'BDBM22561'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H4 receptor (Homo sapiens (Human))	BDBM22561 (2-arylbenzimidazole derivative, 7 | 5-tert-butyl-2...) Show SMILES CN1CCN(CCCOc2ccc(cc2Cl)-c2nc3ccc(cc3[nH]2)C(C)(C)C)CC1 Show InChI InChI=1S/C25H33ClN4O/c1-25(2,3)19-7-8-21-22(17-19)28-24(27-21)18-6-9-23(20(26)16-18)31-15-5-10-30-13-11-29(4)12-14-30/h6-9,16-17H,5,10-15H2,1-4H3,(H,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	65	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human recombinant histamine H4 receptor				Bioorg Med Chem Lett 20: 3367-71 (2010) Article DOI: 10.1016/j.bmcl.2010.04.017 BindingDB Entry DOI: 10.7270/Q23J3D4Z
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM22561 (2-arylbenzimidazole derivative, 7 | 5-tert-butyl-2...) Show SMILES CN1CCN(CCCOc2ccc(cc2Cl)-c2nc3ccc(cc3[nH]2)C(C)(C)C)CC1 Show InChI InChI=1S/C25H33ClN4O/c1-25(2,3)19-7-8-21-22(17-19)28-24(27-21)18-6-9-23(20(26)16-18)31-15-5-10-30-13-11-29(4)12-14-30/h6-9,16-17H,5,10-15H2,1-4H3,(H,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	65	-41.0	n/a	n/a	n/a	n/a	n/a	7.5	25
Johnson & Johnson Pharmaceutical					Assay Description The Ki values were calculated based on an experimentally determined appropriate Kd value according to Cheng and Prusoff.				Bioorg Med Chem Lett 16: 6043-8 (2006) Article DOI: 10.1016/j.bmcl.2006.08.117 BindingDB Entry DOI: 10.7270/Q20P0XB5
					More data for this Ligand-Target Pair