Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Histamine H4 receptor' and Ligand = 'BDBM22565'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H4 receptor (Homo sapiens (Human))	BDBM22565 (2-arylbenzimidazole lead compound 1 | 5-chloro-2-{...) Show SMILES CN1CCN(CCCOc2ccc(cc2)-c2nc3ccc(Cl)cc3[nH]2)CC1 Show InChI InChI=1S/C21H25ClN4O/c1-25-10-12-26(13-11-25)9-2-14-27-18-6-3-16(4-7-18)21-23-19-8-5-17(22)15-20(19)24-21/h3-8,15H,2,9-14H2,1H3,(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Displacement of [3H]histamine from recombinant human histamine H4 receptor				Bioorg Med Chem Lett 21: 6577-81 (2011) Article DOI: 10.1016/j.bmcl.2011.08.014 BindingDB Entry DOI: 10.7270/Q2CN749X
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM22565 (2-arylbenzimidazole lead compound 1 | 5-chloro-2-{...) Show SMILES CN1CCN(CCCOc2ccc(cc2)-c2nc3ccc(Cl)cc3[nH]2)CC1 Show InChI InChI=1S/C21H25ClN4O/c1-25-10-12-26(13-11-25)9-2-14-27-18-6-3-16(4-7-18)21-23-19-8-5-17(22)15-20(19)24-21/h3-8,15H,2,9-14H2,1H3,(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	124	-39.4	n/a	n/a	n/a	n/a	n/a	7.5	25
Johnson & Johnson Pharmaceutical					Assay Description The Ki values were calculated based on an experimentally determined appropriate Kd value according to Cheng and Prusoff.				Bioorg Med Chem Lett 16: 6043-8 (2006) Article DOI: 10.1016/j.bmcl.2006.08.117 BindingDB Entry DOI: 10.7270/Q20P0XB5
					More data for this Ligand-Target Pair