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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine H4 receptor' and Ligand = 'BDBM50137648'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H4 receptor


(Homo sapiens (Human))		BDBM50137648
PNG
(CHEMBL3753784)
Show SMILES COc1ccc(CNc2nc(nc-3c2CCc2ccccc-32)N2CCN(C)CC2)cc1-c1ccc(Cl)cc1
Show InChI InChI=1S/C31H32ClN5O/c1-36-15-17-37(18-16-36)31-34-29-25-6-4-3-5-22(25)10-13-26(29)30(35-31)33-20-21-7-14-28(38-2)27(19-21)23-8-11-24(32)12-9-23/h3-9,11-12,14,19H,10,13,15-18,20H2,1-2H3,(H,33,34,35)
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Similars
Article
PubMed
 1.95E+4n/an/an/an/an/an/an/an/a



Friedrich-Alexander-Universit£t Erlangen-N£rnberg

Curated by ChEMBL


Assay Description
Displacement of [3H]histamine from human histamine 4 receptor expressed in Sf9 cell membranes by liquid scintillation counting

Bioorg Med Chem Lett 26: 292-300 (2016)


Article DOI: 10.1016/j.bmcl.2015.12.035
BindingDB Entry DOI: 10.7270/Q2Z03B0K
More data for this
Ligand-Target Pair