Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine H4 receptor' and Ligand = 'BDBM50319288'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H4 receptor (Homo sapiens (Human))	BDBM50319288 ((+/-)-2-(4-(3-(3,6-diazabicyclo[3.2.0]heptan-3-yl)...) Show SMILES Cc1cc(OCCCN2CC3CNC3C2)ccc1-c1nc2ccc(F)c(C)c2[nH]1 Show InChI InChI=1S/C23H27FN4O/c1-14-10-17(29-9-3-8-28-12-16-11-25-21(16)13-28)4-5-18(14)23-26-20-7-6-19(24)15(2)22(20)27-23/h4-7,10,16,21,25H,3,8-9,11-13H2,1-2H3,(H,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human recombinant histamine H4 receptor				Bioorg Med Chem Lett 20: 3367-71 (2010) Article DOI: 10.1016/j.bmcl.2010.04.017 BindingDB Entry DOI: 10.7270/Q23J3D4Z
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