Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine H4 receptor' and Ligand = 'BDBM50319289'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H4 receptor (Homo sapiens (Human))	BDBM50319289 ((+/-)-2-(4-(3-(3,6-diazabicyclo[3.1.0]hexan-3-yl)p...) Show SMILES Cc1cc(OCCCN2CC3NC3C2)ccc1-c1nc2ccc(F)c(C)c2[nH]1 Show InChI InChI=1S/C22H25FN4O/c1-13-10-15(28-9-3-8-27-11-19-20(12-27)24-19)4-5-16(13)22-25-18-7-6-17(23)14(2)21(18)26-22/h4-7,10,19-20,24H,3,8-9,11-12H2,1-2H3,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human recombinant histamine H4 receptor				Bioorg Med Chem Lett 20: 3367-71 (2010) Article DOI: 10.1016/j.bmcl.2010.04.017 BindingDB Entry DOI: 10.7270/Q23J3D4Z
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