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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine H4 receptor' and Ligand = 'BDBM50356817'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H4 receptor


(Homo sapiens (Human))
BDBM50356817
PNG
(CHEMBL1914783)
Show SMILES CN[C@@H]1CCN(C1)c1nc(N)nc2c3cc(ccc3oc12)C(F)(F)F |r|
Show InChI InChI=1S/C16H16F3N5O/c1-21-9-4-5-24(7-9)14-13-12(22-15(20)23-14)10-6-8(16(17,18)19)2-3-11(10)25-13/h2-3,6,9,21H,4-5,7H2,1H3,(H2,20,22,23)/t9-/m1/s1
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Article
PubMed
1n/an/an/an/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research& Development

Curated by ChEMBL


Assay Description
Displacement of [3H]histamine from recombinant human histamine H4 receptor


Bioorg Med Chem Lett 21: 6577-81 (2011)


Article DOI: 10.1016/j.bmcl.2011.08.014
BindingDB Entry DOI: 10.7270/Q2CN749X
More data for this
Ligand-Target Pair