Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Histamine H4 receptor' and Ligand = 'BDBM50356885'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H4 receptor (Homo sapiens (Human))	BDBM50356885 (CHEMBL1915345) Show SMILES CN1C[C@H]2CN(C[C@H]2C1)C(=O)c1cc2cc(Cl)ccc2[nH]1 |r| Show InChI InChI=1S/C16H18ClN3O/c1-19-6-11-8-20(9-12(11)7-19)16(21)15-5-10-4-13(17)2-3-14(10)18-15/h2-5,11-12,18H,6-9H2,1H3/t11-,12+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human recombinant histamine H4 receptor expressed in CHO cells coexpressing Ga15 by radioligand filtration binding...				Bioorg Med Chem Lett 22: 1156-9 (2012) Article DOI: 10.1016/j.bmcl.2011.11.098 BindingDB Entry DOI: 10.7270/Q2Q81DJD
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50356885 (CHEMBL1915345) Show SMILES CN1C[C@H]2CN(C[C@H]2C1)C(=O)c1cc2cc(Cl)ccc2[nH]1 |r| Show InChI InChI=1S/C16H18ClN3O/c1-19-6-11-8-20(9-12(11)7-19)16(21)15-5-10-4-13(17)2-3-14(10)18-15/h2-5,11-12,18H,6-9H2,1H3/t11-,12+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-histamine from full length human H4R expressed in HEK293 cells				Bioorg Med Chem Lett 21: 6596-602 (2011) Article DOI: 10.1016/j.bmcl.2011.07.125 BindingDB Entry DOI: 10.7270/Q20C4W6C
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50356885 (CHEMBL1915345) Show SMILES CN1C[C@H]2CN(C[C@H]2C1)C(=O)c1cc2cc(Cl)ccc2[nH]1 |r| Show InChI InChI=1S/C16H18ClN3O/c1-19-6-11-8-20(9-12(11)7-19)16(21)15-5-10-4-13(17)2-3-14(10)18-15/h2-5,11-12,18H,6-9H2,1H3/t11-,12+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity at human histamine H4 receptor expressed in HEK293 cells assessed as rev inhibition of forskolin-stimulated cAMP accumulation by ...				Bioorg Med Chem Lett 22: 1156-9 (2012) Article DOI: 10.1016/j.bmcl.2011.11.098 BindingDB Entry DOI: 10.7270/Q2Q81DJD
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50356885 (CHEMBL1915345) Show SMILES CN1C[C@H]2CN(C[C@H]2C1)C(=O)c1cc2cc(Cl)ccc2[nH]1 |r| Show InChI InChI=1S/C16H18ClN3O/c1-19-6-11-8-20(9-12(11)7-19)16(21)15-5-10-4-13(17)2-3-14(10)18-15/h2-5,11-12,18H,6-9H2,1H3/t11-,12+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity at full length human H4R expressed in HEK293 cells assessed as reversal of forskolin-induced cAMP production by CRE-beta-lactamas...				Bioorg Med Chem Lett 21: 6596-602 (2011) Article DOI: 10.1016/j.bmcl.2011.07.125 BindingDB Entry DOI: 10.7270/Q20C4W6C
					More data for this Ligand-Target Pair