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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine H4 receptor' and Ligand = 'BDBM50424331'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H4 receptor


(Homo sapiens (Human))
BDBM50424331
PNG
(CHEMBL2314497)
Show SMILES Nc1nc(N2CCNCC2)c2cc([nH]c2n1)-c1ccc(F)cc1
Show InChI InChI=1S/C16H17FN6/c17-11-3-1-10(2-4-11)13-9-12-14(20-13)21-16(18)22-15(12)23-7-5-19-6-8-23/h1-4,9,19H,5-8H2,(H3,18,20,21,22)
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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
390n/an/an/an/an/an/an/an/a



KU Leuven

Curated by ChEMBL


Assay Description
Displacement of [3H]Histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai/o and Gbeta1gamma


Bioorg Med Chem Lett 23: 132-7 (2012)


Article DOI: 10.1016/j.bmcl.2012.10.139
BindingDB Entry DOI: 10.7270/Q28P61TF
More data for this
Ligand-Target Pair