Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine N-methyltransferase' and Ligand = 'BDBM50110295'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine N-methyltransferase (Rattus norvegicus)	BDBM50110295 ((7-Chloro-quinolin-4-yl)-(6-piperidin-1-yl-hexyl)-...) Show SMILES Clc1ccc2c(NCCCCCCN3CCCCC3)ccnc2c1 Show InChI InChI=1S/C20H28ClN3/c21-17-8-9-18-19(10-12-23-20(18)16-17)22-11-4-1-2-5-13-24-14-6-3-7-15-24/h8-10,12,16H,1-7,11,13-15H2,(H,22,23)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methylhistamine				J Med Chem 45: 1128-41 (2002) BindingDB Entry DOI: 10.7270/Q2H70F4V
					More data for this Ligand-Target Pair