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Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine N-methyltransferase' and Ligand = 'BDBM50110296'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine N-methyltransferase


(Rattus norvegicus)		BDBM50110296
PNG
(CHEMBL14868 | {4-[4-(3-Piperidin-1-yl-propoxy)-phe...)
Show SMILES C(CCc1ccc(OCCCN2CCCCC2)cc1)CNc1c2CCCCc2nc2ccccc12
Show InChI InChI=1S/C31H41N3O/c1-8-21-34(22-9-1)23-10-24-35-26-18-16-25(17-19-26)11-6-7-20-32-31-27-12-2-4-14-29(27)33-30-15-5-3-13-28(30)31/h2,4,12,14,16-19H,1,3,5-11,13,15,20-24H2,(H,32,33)
KEGG

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 48n/an/an/an/an/an/a



Freie Universität Berlin

Curated by ChEMBL


Assay Description
Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methylhistamine

J Med Chem 45: 1128-41 (2002)


BindingDB Entry DOI: 10.7270/Q2H70F4V
More data for this
Ligand-Target Pair