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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine receptor (H3)' and Ligand = 'BDBM50262586'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50262586
PNG
(2-Methyl-3-(4-{[3-(3-methyl-1-pyrrolidinyl)propyl]...)
Show SMILES CC1CCN(CCCOc2ccc(cc2)-n2c(C)nc3ccccc3c2=O)C1
Show InChI InChI=1S/C23H27N3O2/c1-17-12-14-25(16-17)13-5-15-28-20-10-8-19(9-11-20)26-18(2)24-22-7-4-3-6-21(22)23(26)27/h3-4,6-11,17H,5,12-16H2,1-2H3
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5.80n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in CHO-K1 cells


J Med Chem 51: 4780-9 (2008)


Article DOI: 10.1021/jm8003834
BindingDB Entry DOI: 10.7270/Q2FQ9WFW
More data for this
Ligand-Target Pair