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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine receptor (H3)' and Ligand = 'BDBM50274617'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50274617
PNG
(3-(4-[(1-Cyclopentyl-4-piperidinyl)oxy]phenyl)-2-m...)
Show SMILES Cc1nc2ccccc2c(=O)n1-c1ccc(OC2CCN(CC2)C2CCCC2)cc1
Show InChI InChI=1S/C25H29N3O2/c1-18-26-24-9-5-4-8-23(24)25(29)28(18)20-10-12-21(13-11-20)30-22-14-16-27(17-15-22)19-6-2-3-7-19/h4-5,8-13,19,22H,2-3,6-7,14-17H2,1H3
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.20n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Antagonist activity at human cloned histamine H3 receptor expressed in CHO-K1 cells assessed as inhibition of R-alpha-methylhistamine-induced [35S]GT...


J Med Chem 51: 6889-901 (2008)


Article DOI: 10.1021/jm800569w
BindingDB Entry DOI: 10.7270/Q27P8Z60
More data for this
Ligand-Target Pair