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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine receptor (H3)' and Ligand = 'BDBM50274653'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50274653
PNG
(3-(4-[(1-Cyclopentyl-4-azepanyl)oxy]phenyl)-2-meth...)
Show SMILES Cc1nc2ccccc2c(=O)n1-c1ccc(OC2CCCN(CC2)C2CCCC2)cc1
Show InChI InChI=1S/C26H31N3O2/c1-19-27-25-11-5-4-10-24(25)26(30)29(19)21-12-14-23(15-13-21)31-22-9-6-17-28(18-16-22)20-7-2-3-8-20/h4-5,10-15,20,22H,2-3,6-9,16-18H2,1H3
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 7n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Antagonist activity at human cloned histamine H3 receptor expressed in CHO-K1 cells assessed as inhibition of R-alpha-methylhistamine-induced [35S]GT...


J Med Chem 51: 6889-901 (2008)


Article DOI: 10.1021/jm800569w
BindingDB Entry DOI: 10.7270/Q27P8Z60
More data for this
Ligand-Target Pair