Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histone chaperone ASF1A' and Ligand = 'BDBM50101674'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone chaperone ASF1A (Homo sapiens (Human))	BDBM50101674 (CHEMBL3394923) Show SMILES COc1cc(CCNC(=O)c2ccc(NC(=O)c3ccccc3)cc2)cc(Br)c1O Show InChI InChI=1S/C23H21BrN2O4/c1-30-20-14-15(13-19(24)21(20)27)11-12-25-22(28)17-7-9-18(10-8-17)26-23(29)16-5-3-2-4-6-16/h2-10,13-14,27H,11-12H2,1H3,(H,25,28)(H,26,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Colorado State University Curated by ChEMBL					Assay Description Inhibition of His-tagged human Asf1a binding with H3/H4 assessed as fluorescence intensity after 30 mins by ALPHA assay				Bioorg Med Chem Lett 25: 963-8 (2015) Article DOI: 10.1016/j.bmcl.2014.11.067 BindingDB Entry DOI: 10.7270/Q2VM4F0G
					More data for this Ligand-Target Pair