BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Histone deacetylase' and Ligand = 'BDBM50117090'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Histone deacetylase (Homo sapiens (Human))	BDBM50117090 ((E,E)-Psammaplin A \| 3-(3-Bromo-4-hydroxy-phenyl)-...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of HDAC in human HeLa cells using Fluor deLys as substrate assessed as deacetylation of substrate by fluorescence assay				Bioorg Med Chem Lett 26: 4372-6 (2016) Article DOI: 10.1016/j.bmcl.2015.12.094 BindingDB Entry DOI: 10.7270/Q2SN0DF3
Shenyang Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase (Homo sapiens (Human))	BDBM50117090 ((E,E)-Psammaplin A \| 3-(3-Bromo-4-hydroxy-phenyl)-...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of HDAC in human HeLa cells using Fluor deLys as substrate assessed as deacetylation of substrate by fluorescence assay				Bioorg Med Chem Lett 26: 4372-6 (2016) Article DOI: 10.1016/j.bmcl.2015.12.094 BindingDB Entry DOI: 10.7270/Q2SN0DF3
Shenyang Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair