Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Histone deacetylase 1 (Homo sapiens (Human)) | BDBM22164 ((3R,5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylca...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | US Patent | n/a | n/a | 1.11E+4 | n/a | n/a | n/a | n/a | n/a | 25 |
ACADEMIA SINICA; NATIONAL TAIWAN UNIVERSITY US Patent | Assay Description The HDAC activity was performed using the HDAC fluorescent activity assay kit (BIOMOL, Plymouth Meeting, Pa., USA) according to the manufacturer'... | US Patent US9353061 (2016) BindingDB Entry DOI: 10.7270/Q2C24V9M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 1 (Homo sapiens (Human)) | BDBM22164 ((3R,5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylca...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.16E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
National Taiwan University Curated by ChEMBL | Assay Description Inhibition of recombinant HDAC1 (unknown origin) after 10 mins by fluorimetric analysis | J Med Chem 56: 3645-55 (2013) Article DOI: 10.1021/jm400179b BindingDB Entry DOI: 10.7270/Q2542PXP | |||||||||||
More data for this Ligand-Target Pair |