Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Histone deacetylase 1' and Ligand = 'BDBM239061'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM239061 (US10227295, Compound 9c | US9409858, 9c | US975183...) Show SMILES Cc1cc(NC(=O)NCc2ccc(cc2)C(=O)NO)no1 Show InChI InChI=1S/C13H14N4O4/c1-8-6-11(17-21-8)15-13(19)14-7-9-2-4-10(5-3-9)12(18)16-20/h2-6,20H,7H2,1H3,(H,16,18)(H2,14,15,17,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	8.0	n/a
H. Lee Moffitt Cancer Center and Research Institute, Inc.; Board of Trustees of the University of Illinois US Patent					Assay Description HDAC inhibition assays were performed by Reaction Biology Corp. (Malvern, Pa.) using isolated human, recombinant full-length HDAC1 and -6 from a bacu...				US Patent US9409858 (2016) BindingDB Entry DOI: 10.7270/Q21V5CWN
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM239061 (US10227295, Compound 9c | US9409858, 9c | US975183...) Show SMILES Cc1cc(NC(=O)NCc2ccc(cc2)C(=O)NO)no1 Show InChI InChI=1S/C13H14N4O4/c1-8-6-11(17-21-8)15-13(19)14-7-9-2-4-10(5-3-9)12(18)16-20/h2-6,20H,7H2,1H3,(H,16,18)(H2,14,15,17,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
KuDOS Pharmaceuticals Ltd.					Assay Description HDAC inhibition assays were performed by Reaction Biology Corp. (Malvern, Pa.) using isolated human, recombinant full-length HDAC1 and -6 from a bacu...				J Med Chem 51: 6581-91 (2008) BindingDB Entry DOI: 10.7270/Q2BZ68CW
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM239061 (US10227295, Compound 9c | US9409858, 9c | US975183...) Show SMILES Cc1cc(NC(=O)NCc2ccc(cc2)C(=O)NO)no1 Show InChI InChI=1S/C13H14N4O4/c1-8-6-11(17-21-8)15-13(19)14-7-9-2-4-10(5-3-9)12(18)16-20/h2-6,20H,7H2,1H3,(H,16,18)(H2,14,15,17,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vernalis (R&D) Ltd					Assay Description HDAC inhibition assays were performed by Reaction Biology Corp. (Malvern, Pa.) using isolated human, recombinant full-length HDAC1 and -6 from a bacu...				J Med Chem 51: 196-218 (2008) BindingDB Entry DOI: 10.7270/Q2VD71RF
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM239061 (US10227295, Compound 9c | US9409858, 9c | US975183...) Show SMILES Cc1cc(NC(=O)NCc2ccc(cc2)C(=O)NO)no1 Show InChI InChI=1S/C13H14N4O4/c1-8-6-11(17-21-8)15-13(19)14-7-9-2-4-10(5-3-9)12(18)16-20/h2-6,20H,7H2,1H3,(H,16,18)(H2,14,15,17,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
H. Lee Moffitt Cancer Center and Research Institute, Inc.; Board of Trustees of the University of Illinois US Patent					Assay Description HDAC inhibition assays were performed by Reaction Biology Corp. (Malvern, Pa.) using isolated human, recombinant full-length HDAC1 and -6 from a bacu...				US Patent US9751832 (2017) BindingDB Entry DOI: 10.7270/Q23T9KBR
					More data for this Ligand-Target Pair