Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Histone deacetylase 1' and Ligand = 'BDBM50105693'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50105693 ((E)-N-Hydroxy-3-[4-(4-sulfamoyl-benzenesulfonylami...) Show SMILES NS(=O)(=O)c1ccc(cc1)S(=O)(=O)Nc1ccc(\C=C\C(=O)NO)cc1 Show InChI InChI=1S/C15H15N3O6S2/c16-25(21,22)13-6-8-14(9-7-13)26(23,24)18-12-4-1-11(2-5-12)3-10-15(19)17-20/h1-10,18,20H,(H,17,19)(H2,16,21,22)/b10-3+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	37
Methylgene Inc. US Patent					Assay Description For deacetylase assays, 20,000 cpm of the [3H]-metabolically labeled acetylated histone substrate (M. Yoshida et al., J. Biol. Chem. 265(28): 17174-1...				US Patent US8796330 (2014) BindingDB Entry DOI: 10.7270/Q22B8WQW
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50105693 ((E)-N-Hydroxy-3-[4-(4-sulfamoyl-benzenesulfonylami...) Show SMILES NS(=O)(=O)c1ccc(cc1)S(=O)(=O)Nc1ccc(\C=C\C(=O)NO)cc1 Show InChI InChI=1S/C15H15N3O6S2/c16-25(21,22)13-6-8-14(9-7-13)26(23,24)18-12-4-1-11(2-5-12)3-10-15(19)17-20/h1-10,18,20H,(H,17,19)(H2,16,21,22)/b10-3+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
MethylGene Inc. Curated by ChEMBL					Assay Description Concentration of compound required for acetylation of histone-4 in human T24 cancer cells				Bioorg Med Chem Lett 11: 2847-50 (2001) BindingDB Entry DOI: 10.7270/Q2SF2VF5
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50105693 ((E)-N-Hydroxy-3-[4-(4-sulfamoyl-benzenesulfonylami...) Show SMILES NS(=O)(=O)c1ccc(cc1)S(=O)(=O)Nc1ccc(\C=C\C(=O)NO)cc1 Show InChI InChI=1S/C15H15N3O6S2/c16-25(21,22)13-6-8-14(9-7-13)26(23,24)18-12-4-1-11(2-5-12)3-10-15(19)17-20/h1-10,18,20H,(H,17,19)(H2,16,21,22)/b10-3+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a
MethylGene Inc. Curated by ChEMBL					Assay Description Concentration of compound required for acetylation of histone-4 in human T24 cancer cells				Bioorg Med Chem Lett 11: 2847-50 (2001) BindingDB Entry DOI: 10.7270/Q2SF2VF5
					More data for this Ligand-Target Pair