Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histone deacetylase 1' and Ligand = 'BDBM50137845'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50137845 (6-(5-Methyl-1,3-dioxo-1,3-dihydro-isoindol-2-yl)-h...) Show SMILES Cc1ccc2C(=O)N(CCCCCC(=O)Nc3ccccc3N)C(=O)c2c1 Show InChI InChI=1S/C21H23N3O3/c1-14-10-11-15-16(13-14)21(27)24(20(15)26)12-6-2-3-9-19(25)23-18-8-5-4-7-17(18)22/h4-5,7-8,10-11,13H,2-3,6,9,12,22H2,1H3,(H,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
MethylGene Inc. Curated by ChEMBL					Assay Description Ability to inhibit recombinant human histone deacetylase 1 (HDAC-1).				Bioorg Med Chem Lett 14: 283-7 (2003) BindingDB Entry DOI: 10.7270/Q2BV7G17
					More data for this Ligand-Target Pair