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Found 1 hit Enz. Inhib. hit(s) with Target = 'Histone deacetylase 1' and Ligand = 'BDBM50232362'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histone deacetylase 1


(Homo sapiens (Human))		BDBM50232362
PNG
(CHEMBL4079799)
Show SMILES CN(C)Cc1c(C)n(Cc2ccc(\C=C\C(=O)NO)cc2)c2ccccc12
Show InChI InChI=1S/C22H25N3O2/c1-16-20(15-24(2)3)19-6-4-5-7-21(19)25(16)14-18-10-8-17(9-11-18)12-13-22(26)23-27/h4-13,27H,14-15H2,1-3H3,(H,23,26)/b13-12+
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Similars
Article
PubMed
n/an/a 2.13E+3n/an/an/an/an/an/a



Taipei Medical University

Curated by ChEMBL


Assay Description
Inhibition of full length human recombinant C-terminal FLAG-His-tagged HDAC1 expressed in Sf21 cells using RHKK(Ac) as substrate after 60 mins by flu...

Eur J Med Chem 127: 115-127 (2017)


Article DOI: 10.1016/j.ejmech.2016.12.039
BindingDB Entry DOI: 10.7270/Q20K2BT4
More data for this
Ligand-Target Pair