Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Histone deacetylase 1' and Ligand = 'BDBM50232652'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50232652 (4-((1H-benzo[d]imidazol-2-ylamino)methyl)-N-(2-ami...) Show SMILES Nc1ccccc1NC(=O)c1ccc(CNc2nc3ccccc3[nH]2)cc1 Show InChI InChI=1S/C21H19N5O/c22-16-5-1-2-6-17(16)24-20(27)15-11-9-14(10-12-15)13-23-21-25-18-7-3-4-8-19(18)26-21/h1-12H,13,22H2,(H,24,27)(H2,23,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
MethylGene Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant HDAC1				Bioorg Med Chem Lett 18: 1502-6 (2008) Article DOI: 10.1016/j.bmcl.2007.12.057 BindingDB Entry DOI: 10.7270/Q2416WT0
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50232652 (4-((1H-benzo[d]imidazol-2-ylamino)methyl)-N-(2-ami...) Show SMILES Nc1ccccc1NC(=O)c1ccc(CNc2nc3ccccc3[nH]2)cc1 Show InChI InChI=1S/C21H19N5O/c22-16-5-1-2-6-17(16)24-20(27)15-11-9-14(10-12-15)13-23-21-25-18-7-3-4-8-19(18)26-21/h1-12H,13,22H2,(H,24,27)(H2,23,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
MethylGene Inc. Curated by ChEMBL					Assay Description Inhibition of HDAC1 in human T24 cells assessed as induction of histone H4 acetylation after 16 hrs relative to MS-275				Bioorg Med Chem Lett 18: 1502-6 (2008) Article DOI: 10.1016/j.bmcl.2007.12.057 BindingDB Entry DOI: 10.7270/Q2416WT0
					More data for this Ligand-Target Pair