BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Histone deacetylase 1' and Ligand = 'BDBM50334366'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50334366 (CHEMBL1643308 \| N-(2-aminophenyl)-3-(4-(1-(2-morph...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Roche R&D Center-China Ltd. Curated by ChEMBL					Assay Description Inhibition of HDAC1 using p53 (379 to 382 residues) based fluorogenic peptide substrate				J Med Chem 55: 8903-25 (2012) Article DOI: 10.1021/jm3011838 BindingDB Entry DOI: 10.7270/Q2TT4S3Q
Roche R&D Center-China Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50334366 (CHEMBL1643308 \| N-(2-aminophenyl)-3-(4-(1-(2-morph...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Roche R&D Center China Ltd Curated by ChEMBL					Assay Description Inhibition of HDAC1				Bioorg Med Chem Lett 21: 110-6 (2010) Article DOI: 10.1016/j.bmcl.2010.11.063 BindingDB Entry DOI: 10.7270/Q2S182S8
Roche R&D Center China Ltd Curated by ChEMBL					More data for this Ligand-Target Pair