Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histone deacetylase 1' and Ligand = 'BDBM50373673'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50373673 (CHEMBL258297) Show SMILES Nc1ccccc1NC(=O)c1ccc(CNc2nc(NC3Cc4ccccc4C3)nc(n2)N2CCOCC2)cc1 Show InChI InChI=1S/C30H32N8O2/c31-25-7-3-4-8-26(25)34-27(39)21-11-9-20(10-12-21)19-32-28-35-29(37-30(36-28)38-13-15-40-16-14-38)33-24-17-22-5-1-2-6-23(22)18-24/h1-12,24H,13-19,31H2,(H,34,39)(H2,32,33,35,36,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
MethylGene Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC1				Bioorg Med Chem Lett 18: 1067-71 (2008) Article DOI: 10.1016/j.bmcl.2007.12.009 BindingDB Entry DOI: 10.7270/Q2ZW1MSD
					More data for this Ligand-Target Pair