BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Histone deacetylase 2' and Ligand = 'BDBM22164'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Histone deacetylase 2 (Homo sapiens (Human))	BDBM22164 ((3R,5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylca...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of recombinant HDAC2 (unknown origin) after 10 mins by fluorimetric analysis				J Med Chem 56: 3645-55 (2013) Article DOI: 10.1021/jm400179b BindingDB Entry DOI: 10.7270/Q2542PXP
National Taiwan University Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM22164 ((3R,5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylca...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	US Patent	n/a	n/a	2.25E+4	n/a	n/a	n/a	n/a	n/a	25
ACADEMIA SINICA; NATIONAL TAIWAN UNIVERSITY US Patent					Assay Description The HDAC activity was performed using the HDAC fluorescent activity assay kit (BIOMOL, Plymouth Meeting, Pa., USA) according to the manufacturer'...				US Patent US9353061 (2016) BindingDB Entry DOI: 10.7270/Q2C24V9M
ACADEMIA SINICA; NATIONAL TAIWAN UNIVERSITY US Patent					More data for this Ligand-Target Pair