Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Histone deacetylase 4 (Homo sapiens (Human)) | BDBM293916 ((S)-1-(3,4-Difluoro-2- methylphenyl)-N- hydroxy-3-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
CHDI Foundation, Inc. US Patent | Assay Description 2 μl (200×) of each diluted solution and each control (full activity: 100% DMSO alone or full inhibition 1 mM) is stamped into V-bottomed polypr... | US Patent US9617259 (2017) BindingDB Entry DOI: 10.7270/Q2DN4743 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 4 (Homo sapiens (Human)) | BDBM293916 ((S)-1-(3,4-Difluoro-2- methylphenyl)-N- hydroxy-3-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
CHDI FOUNDATION, INC. US Patent | Assay Description 5 μl of each solution of 1:20 diluted compound from above is transferred to a clear bottomed, black, 384-well assay plate using the Bravo or the... | US Patent US10106535 (2018) BindingDB Entry DOI: 10.7270/Q2F47R6G | |||||||||||
More data for this Ligand-Target Pair |