Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histone deacetylase 4' and Ligand = 'BDBM344365'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 4 (Homo sapiens (Human))	BDBM344365 ((1S,3S*)-3-(1- (Difluoromethyl)-1H- indazol-6-yl)-...) Show SMILES Cc1c(F)cccc1[C@@]1(CC[C@@H](C1)c1ccc2cnn(C(F)F)c2c1)C(=O)NO |r| Show InChI InChI=1S/C21H20F3N3O2/c1-12-16(3-2-4-17(12)22)21(19(28)26-29)8-7-14(10-21)13-5-6-15-11-25-27(20(23)24)18(15)9-13/h2-6,9,11,14,20,29H,7-8,10H2,1H3,(H,26,28)/t14-,21-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...				US Patent US9783488 (2017) BindingDB Entry DOI: 10.7270/Q2JH3P96
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