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Found 1 hit Enz. Inhib. hit(s) with Target = 'Histone deacetylase 4' and Ligand = 'BDBM50300454'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histone deacetylase 4


(Homo sapiens (Human))		BDBM50300454
PNG
(CHEMBL574378 | N-hydroxy-2,2-bis(4-(methylsulfonam...)
Show SMILES CS(=O)(=O)Nc1ccc(cc1)C(C(=O)NO)c1ccc(NS(C)(=O)=O)cc1
Show InChI InChI=1S/C16H19N3O6S2/c1-26(22,23)18-13-7-3-11(4-8-13)15(16(20)17-21)12-5-9-14(10-6-12)19-27(2,24)25/h3-10,15,18-19,21H,1-2H3,(H,17,20)
PDB
MMDB

KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



MethylGene Inc.

Curated by ChEMBL


Assay Description
Inhibition of human recombinant N-terminal FLAG-tagged HDAC4 (612-1034) expressed in baculovirus after 10 mins by fluorimetric analysis

Bioorg Med Chem Lett 19: 5684-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.08.010
BindingDB Entry DOI: 10.7270/Q2NZ87QH
More data for this
Ligand-Target Pair