Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Histone deacetylase 5 (Homo sapiens (Human)) | BDBM32188 (CLIOQUINOL | Clioquinol (CQ) | TG2-36-2 | cid_2788) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | 3.04E+4 | n/a | n/a | n/a | n/a | 8.0 | n/a |
Soochow University | Assay Description Briefly, recombinant HDACs and substrates were diluted in reaction buffer (50 mM Tris-HCl, pH 8.0, 137 mM NaCl, 2.7mM KCl, 1mM MgCl2, 1 mg/ml BSA, 1%... | J Biol Chem 288: 34181-9 (2013) Article DOI: 10.1074/jbc.M113.472563 BindingDB Entry DOI: 10.7270/Q2668C1K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 5 (Homo sapiens (Human)) | BDBM32188 (CLIOQUINOL | Clioquinol (CQ) | TG2-36-2 | cid_2788) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | 3.07E+4 | n/a | n/a | n/a | n/a | 8.0 | n/a |
Soochow University | Assay Description Briefly, recombinant HDACs and substrates were diluted in reaction buffer (50 mM Tris-HCl, pH 8.0, 137 mM NaCl, 2.7mM KCl, 1mM MgCl2, 1 mg/ml BSA, 1%... | J Biol Chem 288: 34181-9 (2013) Article DOI: 10.1074/jbc.M113.472563 BindingDB Entry DOI: 10.7270/Q2668C1K | |||||||||||
More data for this Ligand-Target Pair |